The podcast episodes provided focus extensively on the life, strategies, and legacy of Alexander Hamilton, exploring his pivotal role in the early United States.

The episodes delve into Hamilton's controversial plans to increase public debt as a way to bind wealthy Americans to the new nation's interests ('A new book examines Alexander Hamilton's plan for public debt'), as well as analyzing the lessons and success strategies that can be drawn from his life and accomplishments (''The Hamilton Guide to Taking Over the World (preview)'').

The episodes also cover Hamilton's complex relationships, personal struggles, and tragic duel with Aaron Burr that ended his life (''The Legacy of Alexander Hamilton''), as well as his influential role as a Federalist leader and kingmaker whose strategic decisions impacted the outcome of the pivotal 1800 presidential election (''American Elections: 1800'').