The podcast episodes provided discuss various aspects of antidepressant use, including the challenges of managing mental health with antidepressants, the impact on sexual function, and the use of antidepressants like bupropion (Wellbutrin) to aid in quitting nicotine addiction.

For example, episode 205. A mental health update focuses on a person's decision to come off antidepressants after over three years of use, and the associated challenges. Episode Best Of: Love, Lust & Lexapro explores the common struggle of balancing mental health treatment with a healthy sex life, as antidepressants often diminish sexual desire. Additionally, episode Nicotine's Effects on the Brain & Body & How to Quit Smoking or Vaping discusses how antidepressants like bupropion can help manage nicotine withdrawal symptoms.