The topic of brain trauma is closely tied to the podcast episodes provided, as they discuss the potential impact of brain injuries on the behavior and actions of the individuals involved.

In the episode "223 - The Infamous Interrogation of Ryan Waller", the hosts discuss how Ryan Waller's brain trauma from being shot in the head led to his incoherent behavior during the interrogation and caused permanent disabilities.

Similarly, the episode "Johnny Lewis" explores the possibility that the actor Johnny Lewis may have been suffering from a traumatic brain injury, which could have contributed to his violent and erratic behavior that culminated in the murder of his landlord.