The podcast episodes highlight that creating a calorie deficit is an essential component of weight loss, as the body needs to burn more calories than it takes in to shed excess weight.

In Episode 60876: "Do Diets Really Work?", the speaker discusses how individual factors like satiety levels and food preferences can impact the success of different diets, even when a calorie deficit is achieved.

In Episode 58441: "How To Actually Lose Weight", the speaker provides a comprehensive guide to weight loss, emphasizing the importance of understanding the science behind calorie deficits and maintenance calories.

In Episode 57658: "S10 Ask Dr Hazel: Is calorie counting the only way to lose weight?", the speaker explains that while being in a calorie deficit is necessary for weight loss, there are various methods besides calorie counting to achieve this.