The topic of cancer diagnosis is prominently featured in several of the podcast episodes provided, with multiple episodes discussing the personal experiences and impacts of cancer diagnoses.

For example, the episode "Abortion Politics in 2024 with Cecile Richards, former Planned Parenthood President" touches on Cecile Richards' recent brain cancer diagnosis and how it has affected her work as an activist. Similarly, the episode "Ep 863 | Lisa Robertson Faces Surgery After Cancer Diagnosis" focuses extensively on Al Robertson's wife Lisa's breast cancer diagnosis and the family's response.

Other episodes, such as "Catherine, Princess of Wales, reveals cancer diagnosis" and "How Kate Middleton's Disappearance Redefined Monoculture", discuss the impact of high-profile individuals like the Princess of Wales and Kate Middleton revealing their cancer diagnoses.