The April 20th cannabis holiday was invoked at points by the hosts, reflecting part of their perspective and style.
The hosts' experiences with and perspectives on marijuana use are a central topic throughout the episode.
The podcast episodes discuss various aspects of cannabis, including its regulatory landscape, potential medical applications, effects on the brain and body, and societal attitudes.
For example, episode 31116 covers the regulatory environment surrounding cannabis and psychedelics, while episode 12849 explores the science behind cannabis's effects on sleep.
Other episodes, such as 54792 and 53728, discuss cannabis use and culture from a more personal and cultural perspective.