The podcast episodes provided showcase a range of topics where conventional wisdom is challenged or questioned.

For example, in the episode 'Enhance your Wellness with Light | Dr. Alexis Cowan', the host discusses how conventional wisdom around avoiding sunlight and UV exposure may be misguided, presenting evidence that controlled exposure can provide health benefits.

Similarly, the episode 'Morley Robbins on How You Reclaim Your Vitality and Health EP 469' challenges mainstream medical practices, positioning the host's perspective as a relevant topic for discussion.

Other episodes, such as 'Diversify or Diworsify?' and 'Spotlight: This Is Why The Federal Reserve Must Cut Interest Rates At Next Month's Meeting', present contrarian views on investment strategies and monetary policy, respectively, challenging the conventional wisdom in those domains.

The episode 'The Fasting Doctor: "Fasting Cures Obesity!", This Controversial New Drug Melts Fat, Fasting Fixes Hormones! Skip Breakfast!' also takes aim at established approaches to weight loss, particularly the 'calories in, calories out' model, and discusses resistance to the host's ideas from some medical professionals.