The podcast episodes cover creatine supplementation in depth, discussing its benefits, optimal dosing, safety, and use for various fitness and health goals.

Several episodes, such as 2368: Training For A Half Marathon, Optimal Creatine Timing, The Best Compound Exercises, & More (Listener Live Coaching), 2351: Short Workouts Vs. Long Workouts for Gains, When Losing Weight Can be a Bad Idea, What to Do When Squatting Hurts Your Knees & More (Listener Live Coaching), and 2343: Sprinting for Fat Loss, the Benefits of Creatine for Women, Undereating & Joint Health & More, provide in-depth discussions on the role of creatine in enhancing cognitive performance, muscle growth, and longevity.

The episodes also cover the importance of proper timing and dosing of creatine, as well as its application for both men and women.