The topic of 'Diagnosis and treatment' is central to the podcast episodes provided, which explore various mental health and medical conditions and the importance of accurate diagnosis for effective treatment.

For example, the episode "Why ADHD Makes You Feel Broken" discusses the societal misconceptions, cognitive mechanisms, and shame complex that contribute to individuals with ADHD often feeling 'fundamentally broken', and the need for appropriate diagnosis and treatment, particularly for underrepresented populations like girls and women.

Similarly, the episode "Understanding Complex PTSD and Borderline Personality Disorder" emphasizes the importance of distinguishing between complex post-traumatic stress disorder (C-PTSD), post-traumatic stress disorder (PTSD), and borderline personality disorder (BPD) for effective treatment planning.

The episode "This Podcast Will Kill You: Coccidioidomycosis" also explores the challenges in diagnosing and treating the fungal disease coccidioidomycosis, and the need for improved protocols.