The podcast episodes discussed showcase several examples of how DNA analysis has been instrumental in criminal investigations and historical discoveries.

In the episode on the discovery of Richard III's remains, DNA testing played a crucial role in confirming the identity of the skeletal remains. Similarly, in the Wild Crime episode, advanced DNA analysis, including genetic genealogy, was used to identify the victim in the Summit Meadow case after 40 years.

The Forensic Files episode also highlights how DNA evidence, such as a strand of hair, can be used to solve a mystery and identify a perpetrator. Additionally, the Southside Strangler episode demonstrates how DNA evidence and analysis were revolutionary forensic techniques that ultimately led to the identification of the serial killer.