The podcast episodes discuss how combining physical exercise with cognitive challenges can provide greater benefits for brain function, cognitive performance, and mood compared to exercise alone.

For example, Moment 165: This Exercise Enhances Mood, Memory & Concentration: David Raichlen recommends incorporating activities like navigating new routes or exercising outdoors to enhance the cognitive benefits of physical activity.

Additionally, #127: Can Resistance Training Help Prevent Alzheimer's? highlights the potential benefits of resistance training in preventing neurodegenerative diseases like Alzheimer's and dementia, citing research on its effects on the brain and insulin sensitivity.