The involvement of the FBI in cases discussed across these podcast episodes highlights the gravity and complexity of these investigations, particularly when dealing with disappearances and crimes that may cross state or national borders.

In the case of Amy Lynn Bradley's disappearance from a cruise ship, the FBI's participation in the investigation underscores the serious nature of the case and the resources dedicated to solving the mystery of her fate. Episode 158 of Murder in America discusses the FBI's involvement in this case.

Similarly, in the case of Florence Akpialik's disappearance in Nome, Alaska, the podcast Episode 7 of Season 4 of Up and Vanished discusses the claims made by a key figure, Oregon John, about alleged FBI involvement in a cover-up, though the podcast team expresses skepticism about the credibility of these claims.

The potential for increased FBI involvement is also discussed in the bonus Q&A episode of CounterClock, where the family of Bruce Cucchiara, who was murdered, hopes that federal authorities could lead to a more thorough investigation of his case.