The podcast episodes explore the topic of food allergies from various angles, including the rising prevalence, potential causes, biological mechanisms, diagnostic and treatment approaches, and the impact on individuals and communities.

Episodes like "Why Does Everyone Have Food Allergies These Days?", "Ep 252: Jason Mantzoukas", and "Raising inclusive kids: Why food allergies should matter to everyone" dive deep into the multifaceted nature of food allergies, examining historical trends, personal experiences, and strategies for fostering greater awareness and inclusion.

The episodes also touch on related topics such as food intolerances, anaphylaxis, allergy research, and the role of the environment, genetics, and the gut microbiome in the development of food allergies.