The podcast episodes discuss the personal health struggles faced by the guests, including Sarah Hyland's experiences with chronic illness and kidney transplants during her time on the TV show Modern Family.

Additionally, the episode featuring Sadie Robertson Huff and April Rodgers explores how April's journey with a cancer scare and preventive mastectomy has been a spiritual experience, leading her to find rest and trust in God.

These examples illustrate how the podcast covers a range of health struggles, from physical to mental, and how individuals navigate these challenges in their personal and professional lives.