The city of Indianapolis is a central focus in several of the podcast episodes provided, with references to specific Indianapolis-based events and entities.

In Episode 46183 of The Pat McAfee Show, the episode featured in-depth interviews with country star Kenny Chesney and author/former Navy SEAL Jack Carr, both of whom discussed their connections to Indianapolis, such as Chesney's upcoming concert in the city and the Olympic swimming trials held there.

Additionally, Episode 31490 of Crime Junkie delves into the infamous "LaSalle Street Murders" that took place in Indianapolis in 1971, providing a detailed account of the decades-long investigation and eventual resolution of the case.