The podcast episodes provided cover several cases where interrogation tactics, particularly those used by law enforcement, have come under scrutiny as potential contributors to wrongful convictions, false confessions, and other issues within the criminal justice system.

For example, the episode "After Serving Decades in Prison for Murder, Two Men Fought to Clear Their Names" examines how police interrogation methods used on the teenage suspects, such as denying access to attorneys and families, may have played a role in their convictions.

Similarly, the "The Spy Who Wouldn't Lie" episode discusses the Gestapo's harsh interrogation methods, including torture and psychological manipulation, during World War II.

The "Just Say You're Sorry" and "The Serial Killer Whisperer" episodes from the "Smoke Screen" podcast delve deeply into the controversial interrogation tactics used by Texas Ranger James Holland, exploring the ethical concerns around his ability to extract confessions from suspects.