The podcast episodes provided focus on various aspects of the Marvel Comics universe, ranging from analyses of specific Marvel characters and their scientific origins to discussions about the first Marvel film adaptation, Howard the Duck.

For example, the episode The Monsterfact Omnibus: Marvel Monsters 2 delves into the origins, powers, and real-world parallels of Marvel characters like Swarm, Puff Adder, Man-Thing, and Colossus, while the episode Matinee Monday: Howard the Duck LIVE! (w/ Kristen Schaal) provides a humorous exploration of the 1985 Marvel film adaptation.

The episodes showcase the depth and breadth of the Marvel Comics universe, highlighting its influence on popular culture and the ongoing fascination with its fantastical creatures and narratives.