The concept of moral uncertainty is explored in several of the podcast episodes, as the hosts grapple with the challenges of making cross-species comparisons of welfare and considering the moral relevance of potential future AI systems.

For example, in #182 - Bob Fischer on comparing the welfare of humans, chickens, pigs, octopuses, bees, and more, the episode discusses a project that compared the moral weight and welfare ranges of different species, highlighting the philosophical assumptions and decision theories involved in such comparisons. Similarly, #173 - Jeff Sebo on digital minds, and how to avoid sleepwalking into a major moral catastrophe examines the need to develop new ethical frameworks to address the potential moral status of AI systems.

These episodes underscore the importance of carefully navigating moral uncertainty in the face of complex ethical questions and the need for rigorous philosophical reasoning to inform decision-making.