The podcast episodes provided cover various aspects of product safety, including high-profile incidents that highlighted the need for greater consumer protection and oversight.

For example, the episode "25: The Tylenol Murders | Red Thread" examines how the Tylenol crisis led to significant changes in product packaging and regulations to prevent future tampering. The episode "Ep. 33 | Sunless Burn" looks at how new consumer products, such as highly absorbent tampons, can pose unforeseen health risks without proper safety testing.

Another key focus is the role of consumer advocacy, as seen in the episode "The birth of the modern consumer movement", which discusses Ralph Nader's influential work in pushing for greater automotive safety standards.