The podcast episodes provided discuss various aspects of Sexually Transmitted Infections (STIs), including the development of new prevention methods, the rising prevalence among older adults, the need for destigmatization and open conversations, and the personal experiences of individuals dealing with STIs.

For example, episode 39656 covers the CDC's endorsement of a new 'morning-after pill' for STIs called doxycycline post-exposure prophylaxis (doxypep), while episode 60759 highlights the importance of safe sex practices and awareness of STIs among older adults. Episode 61256 features a creator discussing his personal experiences with STIs like chlamydia, and episode 57051 explores the stigma surrounding herpes and the need for better sexual education.

These episodes demonstrate the multifaceted nature of STIs, from new prevention methods to the societal impact and personal experiences, highlighting the importance of addressing this public health issue.