The podcast episodes provided cover a range of smuggling activities, from the transportation of illegal alcohol during Prohibition in the United States to the smuggling of silkworms out of ancient China, and the modern-day smuggling operations of organized crime groups.

In the episode 'Scofflaws, Moonshiners, Bootleggers, and Crime Lords', the host discusses how enterprising Americans flouted the law during Prohibition to continue drinking, with organized crime groups flourishing in the black market for alcohol. The episode 'The Missing Chums' also mentions a previous smuggling case involving the Hardy Boys.

The podcast episode 'Smuggling Silk Out of China' delves into the history of how the secret to silk production was smuggled out of China, breaking their monopoly on the valuable commodity. Additionally, the episode 'The Most Dangerous Russian Mobster America Has Ever Known: Boris Nayfeld' discusses the various smuggling operations, including drugs, diamonds, and contraband electronics, that the Russian mobster was involved in.

Finally, the episode 'Assassins, Heists, & Nazis - The Untold Story of the Abortion Pill in America' opens with a dramatized scene of individuals smuggling the then-illegal abortion pill into the United States, setting the stage for the covert operations involved in the story.