The topic of 'Struggles and challenges' is prominently featured in the podcast episodes, with both shows exploring the unique difficulties faced by individuals in the entertainment industry and in personal life.

In the episode 'We are the CEOs of Fierceness with Trixie and Katya', the hosts discuss the pressures and demands of their profession as drag queens, including the need to constantly project an image of confidence and fearlessness. The episode highlights the internal struggles that can come with such a public-facing career.

Similarly, the episode 'How to clear negative thoughts and live a positive life' from 'The Positive Mindset Podcast' explores strategies for overcoming negative thought patterns and personal challenges, framing difficulties as opportunities for growth and self-discovery.