The podcast episodes discuss the experiences and care of transgender youth, particularly in the context of recent policy changes and debates surrounding gender-affirming healthcare.

Several episodes delve into the difficulties faced by transgender youth and their families, such as the removal of a child from their home due to lack of gender affirmation "They Took Our Daughter | Todd & Krista Kolstad", as well as the exclusion of minors from new transgender legislation in Finland "Episode 277 UNLOCKED - Trans Rights in Finland".

The episodes also highlight the importance of providing appropriate, evidence-based healthcare and support for transgender youth, while addressing the concerns and misinformation surrounding this issue.