The podcast episodes discuss various unsolved cases, including disappearances, murders, and other mysterious deaths that have yet to be fully resolved despite ongoing investigations and law enforcement efforts.

For example, the case of Justin Gaines' disappearance featured in Introducing: Drowning Creek has remained unsolved for over a decade, despite a confession that has not led to any arrests. Similarly, the Spreckels Mansion deaths discussed in True Crime Vault: Mystery in Coronado and the potential serial killings linked to Kelly Cochran in The Wedding Vow Murder Pact Killers have left many unanswered questions.

These unresolved cases illustrate the challenges law enforcement often face in bringing closure to victims' families and the public, as well as the persistent efforts of investigators, journalists, and podcasters to shed light on these mysteries.