DeepSummary
In this episode, Dr. Nathan Bryan explains why nitric oxide is considered the 'holy grail' molecule for preventing chronic diseases like cardiovascular disease, Alzheimer's, diabetes, and more. He discusses the four hallmarks of disease - low blood flow, inflammation, oxidative stress, and immune dysfunction - and how nitric oxide plays a role in addressing all of them. Dr. Bryan warns about the dangers of long-term use of proton pump inhibitors (PPIs) like Prilosec, which can increase the risk of heart attacks and Alzheimer's by 20-40% by inhibiting nitric oxide production.
Dr. Bryan shares that lifestyle factors like a diet high in sugar, sedentary lifestyle, use of mouthwash/fluoride toothpaste, and lack of sunlight exposure contribute to nitric oxide deficiency. He recommends getting micronutrient testing to identify deficiencies and supplementing accordingly. Additionally, he advocates for filtering home water supplies to avoid contaminants that can make people sick.
To boost nitric oxide levels, Dr. Bryan suggests eating nutrient-dense foods like dark leafy greens, algae products like chlorella and spirulina, and organ meats. He has also developed a nitric oxide-releasing lozenge supplement. For those with advanced disease, he discusses the potential of future nitric oxide drug therapies his company is working on.
Key Episodes Takeaways
- Nitric oxide is considered the 'holy grail' molecule for preventing and treating chronic diseases like cardiovascular disease, Alzheimer's, diabetes, and more.
- The four hallmarks of disease that nitric oxide helps address are low blood flow, inflammation, oxidative stress, and immune dysfunction.
- Long-term use of proton pump inhibitor drugs like Prilosec can increase risk of heart attacks and Alzheimer's by 20-40% by inhibiting nitric oxide production.
- Lifestyle factors like high-sugar diet, sedentary lifestyle, mouthwash use, lack of sun exposure contribute to nitric oxide deficiency.
- Testing for nutrient deficiencies and supplementing accordingly, along with a nutrient-dense diet, can help boost nitric oxide levels.
- Filtering home water is important to avoid contaminants that can deplete nitric oxide.
- While a nitric oxide supplement can help, it is not a panacea - maintaining an overall healthy lifestyle is crucial.
- Future nitric oxide drug therapies may offer more targeted treatments for conditions like heart disease, Alzheimer's and diabetic ulcers.
Top Episodes Quotes
- “Nitric oxide is considered really the holy grail because it's involved in everything we know about the onset and progression of cardiovascular disease, which remains the number one killer of men and women worldwide.“ by Nathan Bryan
- “So shutting down stomach acid production obviously will have unintended consequences. And now we're seeing that come to the fore. And, you know, in 2015, it was first reported that people have been on ppis for three to five years, have anywhere from a 20% to 40% higher incidence of heart attack.“ by Nathan Bryan
- “Nitric oxide is foundational. It's critically important, but it's not a panacea and it's not an end all, be all, cure all, because you still have to address other issues.“ by Nathan Bryan
Entities
Company
Person
Concept
Product
Organization
Episode Information
Dhru Purohit Show
Dhru Purohit
5/29/24