DeepSummary
Corey and Ethan discuss ADHD (Attention Deficit Hyperactivity Disorder), its causes, symptoms, and potential links to the gut microbiome. They explain that ADHD is a neurodevelopmental disorder that affects executive function, attention, and emotional regulation. It is more commonly diagnosed in males and has genetic and environmental factors contributing to its development.
The hosts delve into the microbiome - the collection of microbes in and on the human body - and its importance in various bodily functions. They discuss the gut-brain axis, the bidirectional communication between the gut and brain, and how the gut microbiome may influence neurotransmitter production and potentially play a role in the development of ADHD.
Corey and Ethan explore a study that found differences in the gut microbiome composition of children with ADHD compared to those without. They emphasize that while the link between ADHD and the microbiome is an interesting area of research, the causes are complex and not yet fully understood. They encourage an open-minded approach while seeking evidence-based explanations.
Key Episodes Takeaways
- ADHD is a neurodevelopmental disorder characterized by difficulties with executive function, attention, and emotional regulation.
- ADHD has genetic and environmental factors contributing to its development, and its causes are complex and not fully understood.
- The gut microbiome, the collection of microbes in and on the human body, plays an important role in various bodily functions and may influence brain function through the gut-brain axis.
- A study found differences in the gut microbiome composition of children with ADHD compared to those without, suggesting a potential link between the microbiome and ADHD development.
- An open-minded, evidence-based approach is necessary when exploring the potential connections between ADHD and the microbiome, as the causes are likely multifactorial and not fully elucidated.
- The complexity of biology and the potential for exceptions to rules highlight the need for nuanced and cautious interpretations of scientific findings.
- Maintaining a balance between being open-minded and critically evaluating information is crucial in scientific inquiry.
- Humor and lightheartedness can effectively balance the seriousness of scientific discussions and make complex topics more accessible.
Top Episodes Quotes
- “Look, they ain't caught me yet, all right? Lucky born slipping away and I've been.“ by Corey
- “It's complex. It is difficult to pin anything down as soon as you find an explanation. For one thing, you're probably gonna find some exception to the rule that you.“ by Corey
- “There is a big difference between having an open mind and a hole in the back of your head.“ by Ethan Ruparellia
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Episode Information
Sci Guys
The Sci Guys
6/19/24
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References & Further Reading
https://www.medrxiv.org/content/10.1101/2023.12.18.23300126v1
https://neurosciencenews.com/adhd-microbiome-22941/
https://www.sciencedirect.com/science/article/pii/S0889159123000697
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7830868/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10437823/
https://www.ncbi.nlm.nih.gov/books/NBK441838/
https://www.niehs.nih.gov/health/topics/science/microbiome
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002533
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469458/