The podcast episodes discuss various aspects of ADHD medications, including their development, mechanisms of action, and strategies for using them effectively in complex ADHD cases.

For example, episode "Why ADHD Makes You Feel Broken" examines how ADHD medications, initially developed to address hyperactivity, have varying efficacy between boys and girls. Episode "Combination Therapy: Medication Strategies for Hard-to-Treat Complex ADHD" delves into the use of medication combinations and tailored approaches to manage ADHD symptoms in individuals with coexisting conditions.