The podcasts discuss several ways in which antibodies are involved in medical research and applications.

In episode 27341, 'How the immune system can cause psychosis, and tool use in otters', the topic of autoimmune encephalitis is explored, where the immune system produces antibodies that attack specific brain proteins, leading to psychiatric symptoms.

Episode 3224, 'Paper mills bribe editors to pass peer review, and detecting tumors with a blood draw', covers the use of engineered DNA-binding antibodies as a novel technique to improve the sensitivity of liquid biopsies for cancer detection.