The podcast episodes discuss immunotherapy, which is a novel approach to cancer treatment that aims to leverage the body's own immune system to target and eliminate cancer cells.

Several episodes, such as The Evolution Of Cancer Treatment, Journal Club with Dr. Peter Attia, and #286 - Journal club with Andrew Huberman, explore the history, development, and promise of immunotherapy as a cancer treatment modality.

The episodes also touch on the use of immunotherapy for other conditions, such as autoimmune encephalitis, where the immune system attacks the brain, causing psychiatric symptoms.