The podcast episodes feature segments where the host, Alix Earle, answers questions submitted by her audience on various topics.

For example, in the episode 'Anxiety: From Hospitals to Healing [RE-RUN]', Alix answers questions ranging from 'cheating to staining a boys' sheets'.

In the episode 'This Choice Can Change Everything | Ask Daily Stoic', Ryan Holiday answers questions from the audience related to topics such as ego and insecurity.