The podcast episodes provided discuss the topic of detransitioning, which involves individuals who previously underwent medical treatments or procedures to transition genders and later decided to revert to their biological sex.

Several episodes, such as Ep 1020 | Botched: The Brutality of Trans Mastectomies | Guest: Soren Aldaco, Why Chloe Cole Detransitioned, and The Cost of "Transition," and Detransitioners Fighting Back, with Mary Margaret Olohan and Luka Hein, focus on the personal experiences of detransitioners and the challenges they faced, including medical complications, regret, and the need for advocacy.

Other episodes, like Standing for Truth Amid Left-Wing Lies, Interviews with Mary Margaret Olohan and Jeremy Carl, explore the broader societal and political implications of detransitioning, including the lack of safeguards, the role of medical professionals, and the impact on children and female athletes.