The podcast episodes provided cover various aspects of drug use and addiction, from personal struggles to the larger societal and political impacts.

For example, the episode 'The Breeders with Caryn Ganz' explores how drug use and addiction have influenced the band's history and music, while 'The Sunday Story: Life in the Shadow of the Philippines' Drug War' examines the devastating impacts of the war on drugs in the Philippines.

Other episodes, such as 'Ep 479 - Red Team Vs. Black Team (feat. Lemaire Lee, Nate Marshall, & Shawn Gardini)' and '#646 - DERIC POSTON + EHSAN AHMAD', delve into the personal experiences of comedians and public figures with drug use and addiction.