The podcast episodes discuss peptide therapy as a potential alternative to traditional testosterone replacement therapy (TRT). Peptide therapy is introduced as a more natural approach that can help regulate hormone levels and address the underlying causes of declining testosterone, rather than simply replacing it.

In Episode 60956, 'Does Testosterone Replacement Therapy Destroy Male Fertility?', Dr. Axe highlights the potential side effects of TRT, including infertility, and emphasizes the benefits of peptide therapy as a safer option. Similarly, Episode 16250, 'Hormone Regulation, Modern Medicine, & Personal Well Being Ft. Dr. Craig Koniver & Keli Koniver', covers the guests' perspectives on the use of peptide therapies and their role in personalized, holistic approaches to healthcare.