The episode revolves around the host being a product of sperm donation, and the implications of seeking out the donor.
A central theme is Katz and his newly discovered siblings all being conceived via sperm donation, and the episode delves into the history and ethics of this practice.
The entire episode revolves around the process of selecting a sperm donor, primarily from the perspective of a prospective single mother.
The podcast episodes provided cover various aspects of sperm donation, including the personal experiences of those involved, the ethical and legal considerations, and the broader societal impact.
Several episodes focus on individuals who were conceived through sperm donation, such as Matt Katz's discovery of his biological father and the emotional journey that followed. Other episodes examine the challenges faced by those seeking sperm donors, like Carolyn's struggle to find a Black sperm donor.
The episodes also delve into the lack of regulation and transparency in the sperm donation industry, highlighting issues around donor rights, privacy, and the potential for creating numerous donor-conceived siblings, as seen in The Longest Shortest Time's 'Sperm Series'.