The podcast episodes cover a range of topics related to cognitive enhancement, including the potential benefits of substances like klotho and methylene blue, as well as strategies for leveraging the 'extended mind' concept to improve thinking and problem-solving abilities.

For example, the episode 'A breakthrough in Alzheimer's disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer's disease' discusses the mechanisms of action of the longevity factor klotho and its cognitive enhancement effects in animal and primate studies.

Another episode, 'Methylene Blue | Improved Focus, ATP Production, and Anti-Aging', explores the potential of methylene blue as a nootropic or cognitive enhancer, improving memory, focus, and energy production.

The episode 'The Science Of Getting Out Of Your Head' examines how incorporating physical movement, engaging with the environment, and collaborating with others can enhance cognitive performance and problem-solving.