The podcast episodes provided discuss various aspects of organ transplantation, including the challenges, advancements, and potential solutions to the ongoing organ shortage crisis in the United States.

Several episodes, such as In U.S., Over 100,000 Await Organ Transplants. Are Pig Organs The Solution?, The miracle of organ donation - and a breakthrough for the future, and Organ transplant reforms stalled by lack of funding, focus directly on organ transplantation and explore topics such as the use of genetically modified pig organs, machine perfusion technology to improve organ preservation, and the Biden administration's efforts to reform the organ transplant system.

Other episodes, like EP. 143: Zombie Cells & What To Do About Them, touch on the potential implications of senescent cells and senolytics in the context of organ transplantation, highlighting the potential of using these therapies to improve the quality of donor organs.