The podcast episodes explore how the Tylenol murders in 1982 caused widespread public panic, as people were warned not to consume Tylenol products due to the cyanide-laced capsules that had caused multiple tragic deaths in the Chicago area.

The Red Thread episode specifically examines this public panic and fear, as well as the investigation, theories, and the pharmaceutical industry's response that led to tamper-evident packaging becoming an industry standard.

Similarly, the Blurry Creatures episode suggests that a potential government coverup of the existence of Sasquatch is motivated by the desire to avoid potential public panic if their existence were proven.